Code: 07405
5 x 1 ml
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INTENDED USE
Lupus Anticoagulants (LA) are antibodies of the IgG and IgM type which are directed against a variety of anionic phospholipids. The presence of LA in plasma is increasingly associated with a variety of haemostatic problems such as recurrent foetal loss, thrombocytopenia, unexplained thrombosis and neurological disorders. LA prolongs phospholipid dependant in vitro clotting assays such as the activated partial thromboplastin time (aPTT). The Diagon Dia-DRVVT Confirm kit is intended for the qualitative confirmation of LA in human plasma. The reagent is designed to be used in conjunction with the Dia-DRVVT Screen Kit (Cat.No.:07310) to discriminate between LA, factor deficiencies (II, V or X) or other inhibitors. If the clot time of the patient samples with the DRVVT Screen procedure are greater than 3 standard deviations above the mean of the normal range and are not corrected by mixing studies, a lupus anticoagulant may be present. Under these circumstances, samples should be re-tested using the Dia-DRVVT Confirm Reagent.